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Dr .irit milman krentsis | Stem cells transplantation | Best Researcher Award
Dr .irit milman krentsis ,MD Anderson,United States,
Education :
Research Experience:
Senior Research Scientist, MD Anderson Cancer Center, University of Texas (2022 – present),Principal Investigator: Professor Yair Reisner, Ph.D.,Led research on lung fibrosis, developed knockout and transgenic mouse models, clinical trial protocol establishment, grant and patent writing, published in peer-reviewed journals, presented at international conferences.,Computational Scientist, Stem Cell Transplantation, MD Anderson Cancer Center, University of Texas (2018 – 2022),Established new lab facility, managed budget, built and trained a team, managed lung fibrosis research projects, published in peer-reviewed journals, presented at international conferences.,Postdoctoral Fellow, Weizmann Institute of Science (2017-2018),Principal Investigator: Professor Yair Reisner, Ph.D.,Conducted research on stem cell differentiation, 3D lung organoids, lung therapy protocols, and roles of Thrombin and Factor VIII in coagulation,Masterās Student, Hebrew University of Jerusalem (2007-2009),Ph.D. Research Advisor: Professor Stella Mitrani Rosenbaum, Ph.D.,Dissertation: “Investigation the role of GNE gene in mouse embryonic development.”
Technical Skills:
Molecular Biology: Cloning, vector construct designing, PCR, Real-time PCR, DNA library production, Southern blot, RNA library production, microarrays.,Biochemistry: HPLC, Immunoprecipitation, Westerns, 2D-PAGE, iTRAQ, protein extraction and analysis, centrifugation sedimentation, Elisa.,Cell Biology: Flow cytometry, Cell sorting, Image stream, Cytof, live cell imaging, 3D imaging, immunofluorescence, cryostat sectioning, immunohistochemistry, lung pathology.,Assay Development: Lung fibrosis identification, Micro CT and MRI for fibrosis qualification, cell-based assays, drug cytotoxicity assays, human lung cells identification, cryopreservation for clinical trial.,Animal Models: Mouse genomic manipulations, breeding, genotyping, knock out models, xenografts, syngeneic models, allogeneic models, Micro CT, MRI scanning, IVIS, Imaging, irradiation.,Cell Culture: Mammalian cell culture, embryonic stem cells culture, differentiation and expansion, transfections, stable cell line development, cryopreservation.,Computer Skills: Cells Sense, Imaris, Image J, Matlab, Prism, Diva, FlowJo, Excel, Word.
Patents:
- Patent on Multipotent lung progenitor cells for lung regeneration (2018)
- US20200289582A1: Conditioning protocols and use for tissue regeneration (2020)
- Patent on Lung cell transplantation for treatment of lung fibrosis (2022)
Research Focus:
- Immunology, stem cell transplantation, lung fibrosis, embryonic and adult stem cells, organ development, lung regeneration, IPF and COPD treatment.
Skills:
- Extensive writing and submission of articles, abstracts, patents, grants, protocols, SOPs
- Project planning, budgeting, lab facility management, team leading, training
- Strong communication, problem-solving, critical thinking, decision-making
Teaching Experience:
- Project Manager at MD Anderson Cancer Center, mentoring and teaching lab techniques (2018-present)
- High School Project Mentor at Weizmann Institute of Science (2013-2018)
- Staff Manager, content writing and teaching at Alberto (2005-2014)
- Teaching Professor at Ramat Gan College (2014-2015)
- Teaching Professor at Ruppin Marine Academic Center (2009-2012)
Publications :
- Lung cell transplantation for treatment of lung fibrosis” – Science Advance, 2024
- “Primer on Fibroblast Growth Factor 7” – Differentiation, 2024
- “Identification of a multipotent lung progenitor for lung regeneration” – BioRxiv, 2022
- “Lung regeneration by transplantation of allogeneic lung progenitors” – SCTM, 2022
- “Multi-lineage Lung Regeneration by Stem Cell Transplantation” – Cell Reports, 2020
- “Lung Injury Repair by Transplantation of Adult Lung Cells” – SCTM, 2018
- “Preconditioning allows engraftment of mouse and human embryonic lung cells” – Nature Medicine, 2015
- “A novel role for factor VIII and thrombin/PAR1 in regulating hematopoiesis” – Blood, 2013
- “The Proteomic Profile of Hereditary Inclusion Body Myopathy” – Plos One, 2011
- “GNE Is Involved in the Early Development of Skeletal and Cardiac Muscle” – Plos One, 2011