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Assoc. Prof. Dr.Mahshid Malakootian |Molecular Genetics|Best Researcher Award

Principle investigator, Rajaie cardiovascular medical and research Institue,Iran

Assoc. Prof. Dr. Mahshid Malakootian is a distinguished researcher in Molecular Genetics and the recipient of the prestigious Best Researcher Award. She serves as the Principal Investigator at the Rajaie Cardiovascular Medical and Research Institute, Iran. Dr. Malakootian’s groundbreaking work focuses on genetic mechanisms underlying cardiovascular diseases, with a strong emphasis on translational research and innovation. Her contributions to the field have been widely recognized, including numerous publications in high-impact journals and active participation in international conferences.

 

Professional Profiles :

Scopus

Orcid

Google Scholar

🎓 Education :

Dr. Mahshid Malakootian earned her Ph.D. in Molecular Genetics in 2014 from Tarbiat Modares University, Tehran, where her research focused on the expression and functional analysis of long non-coding RNAs during neural differentiation and tumorigenesis. She holds an M.Sc. in Biology: Molecular Genetics (2007) from the same university, with her thesis examining the expression of the Nucleostemin gene in brain tumor tissues. She completed her B.Sc. in Biology: Cellular and Molecular Sciences (2003) at the University of Tehran, where she researched genomic imprinting

 

🏢 Experience:

Dr. Malakootian has extensive post-doctoral research experience, including a fellowship at the Montreal Clinical Research Institute (IRCM) at McGill University, Canada (2016–2017), where she studied PCSK7 RNA regulators in cellular and mouse models. She also conducted research as a post-doctoral fellow at Tarbiat Modares University (2014–2015) and as a visiting research scholar at Case Western Reserve University School of Medicine, USA (2011–2012)..

Skills:

Dr. Malakootian is skilled in molecular biology techniques, bioinformatics analysis, and RNA research. Her expertise spans cardiovascular genetics, cancer biology, stem cell research, and gene regulation, contributing to advancements in diagnostics and therapeutics.

 

Research Focus :

Dr. Malakootian’s research focuses on the molecular mechanisms underlying cardiovascular diseases and cancer, with a particular interest in non-coding RNAs and their roles as diagnostic biomarkers. Her projects include analyzing RNA profiles during stem cell differentiation into cardiomyocytes, studying nucleotide changes in PCSK9 and ANRIL genes, and investigating novel linc-ROR variants for stem cell production.

 

🔬Awards:

Dr. Malakootian has received numerous prestigious awards, including the Best Young Researcher Award from Rajaie Cardiovascular Medical and Research Institute in 2017 and 2019. She received the Top Thesis Award from the Iranian Council of Stem Cell Technology in 2014 and the AACR Scholar-In-Training Award in 2010. She has consistently excelled academically, earning top ranks in national examinations for her Ph.D. studies in Molecular Genetics and Cell and Molecular Biology.

 Publications:

  • MicroRNAs: roles in cardiovascular development and disease
    Citation: 140
    Authors: S. Kalayinia, F. Arjmand, M. Maleki, M. Malakootian, C.P. Singh
    Year: 2021

 

  • Post-transcriptional regulation of PCSK9 by miR-191, miR-222, and miR-224
    Citation: 59
    Authors: P. Naeli, F. Mirzadeh Azad, M. Malakootian, N.G. Seidah, S.J. Mowla
    Year: 2017

 

  • Two lung development-related microRNAs, miR-134 and miR-187, are differentially expressed in lung tumors
    Citation: 32
    Authors: F.M. Azad, P. Naeli, M. Malakootian, A. Baradaran, M. Tavallaei, M. Ghanei, …
    Year: 2016

 

  • Ciprofloxacin removal from aqueous media by adsorption process: a systematic review and meta-analysis
    Citation: 30*
    Authors: N.M. Malakootiana Mahshid, Faraji Maryam, Malakootian Mohammad
    Year: 2021

 

  • Pathophysiology, Diagnosis, Treatment, and Genetics of Carpal Tunnel Syndrome: A Review
    Citation: 27*
    Authors: M. Mahshid, S. Mahdieh, G. Akram, O. Maziar
    Year: 2022

 

  • Linc-ROR and its spliced variants 2 and 4 are significantly up-regulated in esophageal squamous cell carcinoma
    Citation: 27
    Authors: R. Sahebi, M. Malakootian, B. Balalaee, A. Shahryari, M. Khoshnia, …
    Year: 2016

 

  • Overexpression of BMI1, a polycomb group repressor protein, in bladder tumors: a preliminary report
    Citation: 27
    Authors: A.M. Shafaroudi, S.J. Mowla, S.A.M. Ziaee, A.R. Bahrami, Y. Atlasi, …
    Year: 2008

 

  • Differential expression of nucleostemin, a stem cell marker, and its variants in different types of brain tumors
    Citation: 24
    Authors: M. Malakootian, S.J. Mowla, H. Saberi, M.H. Asadi, Y. Atlasi, A.M. Shafaroudi
    Year: 2010

 

  • lncRNA PSORS1C3 is regulated by glucocorticoids and fine-tunes OCT4 expression in non-pluripotent cells
    Citation: 21
    Authors: F. Mirzadeh Azad, M. Malakootian, S.J. Mowla
    Year: 2019

 

  • Novel spliced variants of OCT4, OCT4C and OCT4C1, with distinct expression patterns and functions in pluripotent and tumor cell lines
    Citation: 21
    Authors: M. Malakootian, F.M. Azad, P. Naeli, M. Pakzad, Y. Fouani, E.T. Bajgan, …
    Year: 2017

 

Conclusion:

Dr. Malakootian stands out as a deserving candidate for the award due to her:Groundbreaking discoveries in RNA research.Leadership in cardiovascular genetics research.Proven academic and scholarly excellence.To further enhance her profile for such awards in the future, she can aim to increase her global visibility, broaden her research collaborations, and focus on societal and translational impacts of her research.

Mahshid Malakootian |Molecular Genetics|Best Researcher Award

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